Scientists have uncovered a key reason why more than half of people with chronic kidney disease eventually die from heart-related complications. According to new research, damaged kidneys release a substance into the bloodstream that directly harms the heart.
The discovery, made by researchers at UVA Health and Mount Sinai, could help doctors spot high-risk patients earlier and open the door to new treatments aimed at preventing or slowing heart failure in people with kidney disease. "Kidney and heart disease can develop silently, so they are often discovered only after damage has already been done," said researcher Uta Erdbrügger, MD, an internal medicine physician-scientist with the University of Virginia School of Medicine's Division of Nephrology. "Our findings can help to identify patients at risk for heart failure earlier, enabling earlier treatment and improved outcomes. Know more: Know more: https://www.sciencedaily.com/releases/2026/01/260120095116.htm
