ESPA long-term study found that while a ketogenic diet prevented weight gain, it also triggered major metabolic problems. Mice developed fatty liver disease, abnormal blood fats, and an impaired ability to control blood sugar—especially after reintroducing carbohydrates. Male mice were hit hardest, showing severe liver damage. The results suggest keto’s benefits may come with hidden risks over time.
Researchers from University of Utah Health have published new findings in Science Advances that examine the long-term effects of the ketogenic diet. The results raise fresh questions about whether the diet is safe or effective for improving metabolic health over extended periods. Although the ketogenic diet was first developed as a treatment for epilepsy, it has become widely popular in recent years for weight loss and for managing conditions such as obesity and type 2 diabetes. In this study, scientists used mice to explore how the diet affects metabolism over time, with results pointing to potentially harmful changes in how the body handles fats and carbohydrates.
Know more: https://www.sciencedaily.com/releases/2026/01/260127010144.htm
