People eating minimally processed foods lost twice as much weight as those on ultra-processed diets, even though both diets were nutritionally balanced, and participants could eat freely. This real-world, long-term study revealed that food processing itself—not just nutrients—plays a significant role in shaping body weight and health outcomes.
More weight loss, less craving: minimally processed meals outperform ultra-processed ones, even with the same calories. When given nutritionally matched diets, participants lost twice as much weight eating minimally processed foods compared to ultra-processed foods, suggesting that cutting down on processing could help to sustain a healthy weight long term, finds a new clinical trial led by researchers at UCL and UCLH.
The study, published in Nature Medicine, is the first interventional study comparing ultra-processed food (UPF) and minimally processed food (MPF) diets in 'real world' conditions, as well as being the longest experimental study of a UPF diet to date1.
Know more: https://www.sciencedaily.com/releases/2025/08/250805041616.htm