The futuristic sounding treatment would work by switching on LED lights embedded close to a tumor, which would then activate biotherapeutic drugs.
These new treatments would be highly targeted and more effective than current state-of-the-art cancer immunotherapies.
New research reveals the science behind this innovative idea. It shows how the UEA team have engineered antibody fragments -- which not only 'fuse' with their target but are also light activated.
It means that in future, immunotherapy treatments could be engineered to attack tumors more precisely than ever before. The principal scientist for this study, Dr Amit Sachdeva, from UEA's School of Chemistry, said: "Current cancer treatments like chemotherapy kill cancer cells, but they can also damage healthy cells in your body such as blood and skin cells.
"This means that they can cause side effects including hair loss, feeling tired and sick, and they also put patients at increased risk of picking up infections. There has therefore been a very big drive to create new treatments that are more targeted and don't have these unwanted side-effects.”
Know more: https://www.sciencedaily.com/releases/2023/02/2302...

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