Increased levels of blood fats in people with type 2 diabetes and obesity are more harmful than previously thought, a new study has found.In patients with metabolic diseases, elevated fat levels in the blood create a reaction to cells which damage their structure and function. University of Leeds researchers have discovered that these stressed-out cells give off a signal which can be passed on to other cells. The signals, known as ceramides, may have a protective benefit in the short-term, because they are part of a mechanism designed to reduce stress in the cell. But in metabolic diseases, which are long term conditions, the signals can kill the cells, make symptoms more severe, and worsen the illness.

https://www.sciencedaily.com/releases/2022/04/220401094824.htm

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